Sources

Where the data comes from

Skinceptor is a navigation layer over public scientific resources. The current dataset is curated and static: 48 ingredients, 6 biology maps and 56 studies. It is a demonstration corpus, not an exhaustive index of cosmetic science.

Chemical identity: molecular formula, molecular weight, CID, SMILES and 2D structure images.

Protein and enzyme records for biological targets, including accession numbers and functional annotation.

Gene symbols, official names and identifiers for the genes referenced in networks and topic maps.

Curated human pathway definitions used for the pathway tier of every network.

Gene Ontology

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Standardised biological process terms where a Reactome pathway is not the right level of description.

Chemical entity ontology identifiers for cross-referencing molecules.

PubMed / Europe PMC

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Primary literature. Each curated study links to its PMID or DOI; unverified identifiers link to a title search instead.

Known limitations

  • Coverage is uneven — well-funded ingredients have far more literature than newer actives.
  • Many cosmetic studies are small, short, industry-funded, or in-vitro only; we label these explicitly.
  • Absence of a relationship here means absence from our curated dataset, not absence from science.
  • Nothing here accounts for formulation, concentration, pH, stability or individual biology.